straight blue/black...Green and Red
This seems to be the first dilemma for blue players (both Gushbond'ers and TVKey'ers). The most relevant question I find is: how do you plan to win? The redux 2c Turbo-Tezz lists can get away without permanent removal. Why? Because their win condition works in spite of spheres and chalice. They plan on racing the beaters by having a manabase that ignores wastes (and to a certain extent spheres with grim monolith) and a win condition that works provided it hits the board.
This is a very different case than the gushbond engine. Here you can't ignore spheres, especially if you plan on winning with Tendrils. Your manabase is smaller and weaker. My read is that bounce in the form of hurkyl's recall is best since it gives you a window to try to go off or resolve tinker>bot. There are lists that go more the attrition route with removal and stuff like lightning bolt, but these seem weaker against shops since you don't have a win condition that trumps theirs and even 1-2 lock pieces can heavily influence your ability to function.
TMDbot Eastman had a pretty good list that ran Trygon Predators, Jace and Lotus Cobras, basically a Trygon Tez that swapped out Bobs for the Gushbond engine + Preordain. It had the ability to generate big mana early and put up longterm threats. I think even his pre-board win% against shops was good, in spite of a lower mana count.
2c