Dante wrote:
"If a permanent is indestructible, rules and effects can’t destroy it. Such permanents are not destroyed by lethal damage, and they ignore the lethal-damage state-based effect (see rule 420.5c)."
So that means, if I remember correctly, a Mishra's Factory enchanted w/ Conencrate Land will not die to damage effects. Very good.
Well, I don't see what Consecrate Land has to do exactly with Indestructible, but no a Mishra's Factory enchanted with CL will not be destroyed due to lethal damage.