The point is that they don't care. They will still win if they are going to win, and it won't matter if you have mage or not.
I'm not going to say that cutting twist is a good idea, but I do agree with a couple of ideas conan has put out. Vs. Tps example that he gave is pretty accurate in my opinion. I have been playing tps for some time and a resolved mage naming tendrils doesn't make me happy any more. I can't play the part of combo any more. First I have to duress and then resolve either wish for chain or chain from md. Its much easier for control to stop chain of vapor than tendrils of agony.
Meddling mage isn't a great card, just a decent one. Adding it does change the functionality of the deck but doesn't necessarily make it worse.
To answer your question, yes. I would. I would rather have a game breaking card or a card i can cycle into something good than a Meddling Mage. And while you may not always have Drain mana up on turn 2, you're far more likely to have it than Mage mana. Regardless, just showing Drain is sometimes enough to discourage an opponent, while Mage requires you to tap out and show vulnerability.
I think that meddling mage can produce strong results in a deck packing four duress. Tapping out to mage after a turn one duress is not a negative play; a resolved mage isn't gamebreaking but it is a positive effect for you.